Lobsang Rinchen vit paisiblement avec ses parents dans un petit village perché en Himalaya. un matin, alors qu'il part retourner les champs accompagné de Gelaï, son petit renard, il fait la connaissance de Makye Ame, la fille du seigneur de Tawang. Une grande amitié naît peu à peu, et le duo devient trio avec l'arrivée de Dédi, la confidente de Makye Ame. Mais pendant ce temps, l'empereur de Chine apprend qu'on lui a caché la mort du 5e dalaï-lama...
Les lamas doivent partir à la recherche de la réincarnation du dalaï-lama et vont bientôt se retrouver à Tawang, bousculant le quotidien de nos trois amis...
Ville natale, Quanzhou J'emprunte toujours des choses à ma propre histoire afin de développer différentes ressources, comme celles de Quanzhou, que ce soit un bateau à voile, la médecine chinoise, le fengshui, ou l'art artisanal des lanternes. Ma ville natale est mon entrepôt.
L'oeuvre L'oeuvre d'art s'apparente au feu d'artifice dans la nuit, lorsqu'elle ne se réalise pas, elle n'est plus qu'un ciel noir...Pour l'artiste, tout est son oeuvre, c'est sa vie. Le problème se pose puisque les gens lèvent les yeux vers le ciel dans la noirceur en l'attente d'un feu d'artifice, et non de l'obscurité.
L'Art Les problèmes de l'art ne peuvent être résolus par l'art, bien que finalement, les problèmes de l'art doivent après tout s'appuyer sur l'art même afin d'être résolus.
L'Artiste L'éducation ne fait pas le bon artiste, mais le bon artiste ressemble plutôt à la bête sauvage. Celles-ci savent dans quel racoin de la forêt faut-il se cacher afin d'attraper sa proie, sans laisser cette dernière s'en apercevoir.
-Cai Guo-Qiang
Generalized Plasticity deals with the plasticity of materials and structures. It is an expansion of the "Unified Strength Theory to Plasticity Theory", leading to a unified treatment of metal plasticity and plasticity of geomaterials, generally. It includes the metal plasticity for Tresca materials, Huber-von-Mises materials and twin-shear materials and the geomaterial plasticity for Mohr-Coulomb materials, generalized twin-shear materials and the Unified Strength Theory.
Asymmetric synthesis remains a challenge to practicing scientists as the need for enantiomerically pure or enriched compounds continues to increase. Over the last decade, a large amount of literature has been published in this field. Principles and Applications of Asymmetric Synthesis consolidates and evaluates the most useful methodologies into a one-volume resource for the convenience of practicing scientists and students.
Authored by internationally renowned scientists in the field, this reliable reference covers more than 450 reactions and includes important stoichiometric as well as catalytic asymmetric reactions. The first chapter reviews the basic principles, common nomenclature, and analytical methods, and the remainder of the book is organized according to reaction type. The text examines such topics as: Carbon-carbon bond formations involving carbonyls, enamines, imines, and enolates
Asymmetric C-O bond formations including epoxidation, dihydroxylation, and aminohydroxylation
Asymmetric synthesis using the Diels-Alder reaction and other cyclizations
Applications to the total synthesis of natural products
Use of enzymes in asymmetric synthesis Practicing chemists in the pharmaceutical, fine chemical, and agricultural professions as well as graduate students will find that Principles and Applications of Asymmetric Synthesis affords comprehensive and current coverage.
An integrated view of chiral drugs?from concept and synthesisto pharmaceutical properties Chirality greatly influences a drug's biological and pharmacological properties. In an effort to achieve more predictable results from chiral drugs, the Food and Drug Administration now requires that these medicines be as pure as possible, which places great demands on drug synthesis, purification, analysis, and testing. To assist researchers in acquiring the essential knowledge to meet these rigid guidelines, Chiral Drugs focuses on three vital chiral technologies?asymmetric synthesis, biocatalytic process, and chiral resolution?to offer details on the basic concepts, key developments, and recent trends in chiral drug discovery, along with: The history of chiral drugs development and industrial applications of chiral technologies A section listing twenty-five approved or advanced-trial chiral drugs that lists each drug name, chemical name and properties, a representative synthetic pathway, pharmacological characterizations, and references An interdisciplinary approach combining synthetic organic chemistry, medicinal chemistry, and pharmacology Nearly two-thirds of the drugs on today's market are chiral drugs. Reducing and eliminating their negative characteristics is an ongoing and serious challenge for the pharmaceutical industry. With its well-balanced approach to covering each important aspect of chirality, Chiral Drugs champions important strategies for tipping the medical scale in a positive direction for the production of more effective?and safer?drugs.
Due to the possibility that petroleum supplies will be exhausted in the next decades to come, more and more attention has been paid to the production of bacterial pl- tics including polyhydroxyalkanoates (PHA), polylactic acid (PLA), poly(butylene succinate) (PBS), biopolyethylene (PE), poly(trimethylene terephthalate) (PTT), and poly(p-phenylene) (PPP). These are well-studied polymers containing at least one monomer synthesized via bacterial transformation. Among them, PHA, PLA and PBS are well known for their biodegradability, whereas PE, PTT and PPP are probably less biodegradable or are less studied in terms of their biodegradability. Over the past years, their properties and appli- tions have been studied in detail and products have been developed. Physical and chemical modifications to reduce their cost or to improve their properties have been conducted. PHA is the only biopolyester family completely synthesized by biological means. They have been investigated by microbiologists, molecular biologists, b- chemists, chemical engineers, chemists, polymer experts, and medical researchers for many years. PHA applications as bioplastics, fine chemicals, implant biomate- als, medicines, and biofuels have been developed. Companies have been est- lished for or involved in PHA related R&D as well as large scale production. It has become clear that PHA and its related technologies form an industrial value chain in fermentation, materials, feeds, and energy to medical fields.
The book synthesizes research on the analysis of biomedical ontologies using formal concept analysis, including through auditing, curation, and enhancement. As the evolution of biomedical ontologies almost inevitably involves manual work, formal methods are a particularly useful tool for ontological engineering and practice, particularly in uncovering unexpected "bugs" and content materials. The book first introduces simple but formalized strategies for discovering undesired and incoherent patterns in ontologies before exploring the application of formal concept analysis for semantic completeness. The book then turns to formal concept analysis, a classical approach used in the mathematical treatment of orders and lattices, as an ontological engineering principle, focusing on the structural property of ontologies with respect to its conformation to lattice or not (non-lattice). The book helpfully covers the development of more efficient algorithms for non-latticedetection and extraction required by exhaustive lattice/non-lattice analysis. The book goes on to highlight the power and utility of uncovering non-lattice structure for debugging ontologies and describes methods that leverage the linguistic information in concept names (labels) for ontological analysis. It also addresses visualization and performance evaluation issues before closing with an overview and forward-looking perspectives on the field. This book is intended for graduate students and researchers interested in biomedical ontologies and their applications. It can be a useful supplement for courses on knowledge representation and engineering and also provide readers with a reference for related scientific publications and literature to assist in identifying potential research topics. All mathematical concepts and notations used in this book can be found in standard discrete mathematics textbooks, and the appendix at the end of the book provides a list of key ontological resources, as well as annotated non-lattice and lattice examples that were discovered using the authors' methods, demonstrating how "bugs are fixed" by converting non-lattices to lattices with minimal edit changes.
This is the first publication to synthesize the fundamental concepts and methodological pursuits behind the art of Cai Guo-Qiang (born 1957), since his 2008 Guggenheim retrospective exhibition catalog I Want to Believe. Introduced through a comprehensive map and chronology and encompassing the visual and textual records from over three decades of Cai Guo-Qiangs career, this book showcases the work of an artist renowned for his unique gunpowder art through his Individuals Journey Through Western Art History. In a series of exhibitions at major museums and cultural sites around the world, including the Prado Museum, Uffizi Galleries, Pushkin State Museum of Fine Arts, National Archaeological Museum of Naples and Pompeii Archaeological Park, and Solomon R. Guggenheim Museum, Cai has engaged in dialogues with periods of Western art history as presented by the institutions. The series also retraces Cais expansive journey of homecoming through dialogues with his original passion for painting, the spirit of Chinese culture and his eternal home in the Cosmos.This publication presents the culmination of Cai?s Journey with the exhibition Odyssey and Homecoming at the Palace Museum, the first ever by a contemporary artist, coinciding with the 600th anniversary of the Forbidden City.
